Ferritin, Serum Level (FERR)

Ferritin is a protein that stores iron and releases it when needed. A serum ferritin test measures the amount of ferritin in the blood to assess iron levels.

Normal Range

• Females: 12–150 ng/mL
• Males: 12–300 ng/mL
• Children: 7–140 ng/mL

Function in the Body

Ferritin plays a crucial role in iron storage and release, ensuring a steady supply for red blood cell production, oxygen transport, and energy metabolism. It also supports immune function and enzymatic processes.

Diseases Revealed by the Test

• Iron Deficiency Anemia: Low ferritin levels indicate depleted iron stores, leading to anemia.
• Hemochromatosis: High ferritin levels suggest iron overload, which can damage organs.
• Chronic Inflammation or Infection: Ferritin levels can be elevated due to ongoing inflammatory conditions.
• Liver Disease: Ferritin is stored in the liver, and abnormal levels can indicate liver dysfunction.

Symptoms

Low Ferritin

• Fatigue
• Dizziness
• Pale skin
• Shortness of breath
• Hair loss

High Ferritin

• Joint pain
• Abdominal pain
• Heart palpitations
• Fatigue

Symptoms of Deficiency and Overdose

• Ferritin Deficiency: Weakness, brittle nails, cold intolerance, headaches.
• Ferritin Overdose: Liver damage, diabetes, heart problems, skin pigmentation.

Diagnosis

• Blood Tests: A ferritin test evaluates iron stores, often combined with iron and transferrin tests.
• Additional Tests: Complete blood count (CBC), liver function tests, and genetic testing for hereditary hemochromatosis may be required.

Frequently Asked Questions

1. Why is the serum ferritin test done?
   It helps diagnose iron-related disorders, anemia, and iron overload conditions.
2. What factors affect ferritin levels?
   Diet, chronic diseases, inflammation, infections, and genetic factors.
3. How can I maintain healthy ferritin levels?
   Consume a balanced diet with adequate iron, avoid excessive iron supplementation, and monitor for symptoms.
4. Can medications affect ferritin levels?
   Yes, iron supplements, anti-inflammatory drugs, and certain chronic disease treatments can alter ferritin levels.
5. What should I do if my ferritin levels are abnormal?
   Consult a doctor for further evaluation, dietary changes, or medical treatment based on underlying conditions.