Anti Streptolysin Antibodies, ASO (ASOT)
Product Description
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What Are ASO?
Anti-Streptolysin O (ASO) antibodies are produced by your immune system in response to infections caused by Group A Streptococcus bacteria. These antibodies specifically bind and neutralize streptolysin O, a toxin released by the bacteria.
Function in the Body
- Neutralize bacterial toxin: ASO antibodies help clear streptolysin O, limiting tissue damage.
- Infection marker: Their presence indicates that the body has recently fought a streptococcal infection.
When to Test
- Suspected strep throat or scarlet fever
- Post-streptococcal complications (e.g., rheumatic fever, glomerulonephritis)
- Persistent or recurrent symptoms after a treated strep infection
Interpreting ASO Levels
ASO Level | Interpretation |
---|---|
High | Recent or ongoing streptococcal infection; may signal post-streptococcal complications |
Normal/Low | No recent exposure to Group A Streptococcus; infection has either not occurred or has long resolved |
Note: ASO levels often remain elevated for weeks to months after an infection clears.
Symptoms & Complications
- Excess ASO: Suggests recent infection; may correlate with rheumatic fever (joint pain, heart inflammation) or glomerulonephritis (blood in urine, swelling).
- Low/Normal ASO: No direct symptoms; reflects absence of recent streptococcal exposure.
How the Test Is Performed
- Blood draw: A simple venous sample.
- Laboratory assay: Quantifies ASO concentration (IU/mL).
- Follow-up: Repeat testing 2–4 weeks later can track rising or falling antibody levels.
FAQs
- What does a high ASO level mean?
Indicates a recent or active Group A Streptococcus infection or a post-streptococcal complication. - Do I need to fast before the test?
No, fasting is not required. - Can ASO levels be elevated for other reasons?
Rarely—some non-streptococcal infections or chronic conditions may cause mild elevations. - How long do ASO levels stay high?
Levels can remain elevated for several weeks to months after infection. - How can I support my immune response?
Maintain a balanced diet rich in vitamins (C, D) and minerals (zinc), stay hydrated, and manage stress.
Why It Matters
Timely ASO testing helps confirm streptococcal infections and prevent serious sequelae like rheumatic fever. Always interpret ASO results alongside clinical signs, throat cultures, or rapid antigen tests to guide appropriate treatment.
Function in the Body
Symptoms of Deficiency
Symptoms of Overdose
Diagnosis
More Information
Frequently Asked Questions
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